https://mhjns.widyagamahusada.ac.id/index.php/mhjns/issue/feed 2026-07-01T14:18:02+07:00 Abdul Qodir, S. Kep., Ns. M. Kep. abdulqodir@widyagamahusada.ac.id Open Journal Systems <p style="margin: 0cm; margin-bottom: .0001pt; text-align: justify; line-height: 150%;"><strong><img style="float: left; width: 243px; margin-top: 8px; margin-right: 10px; border: 2px solid #184b80;" src="https://mhjns.widyagamahusada.ac.id/public/site/images/ojsadmin/mhjns02a231.png" alt="" width="231" height="346" /></strong></p> <p style="margin: 0cm; margin-bottom: .0001pt; text-align: justify; line-height: 150%;"><strong>Media Husada Jurnal of Nursing Science (MHJNS)</strong> is a peer-reviewed, open access journal which publishes original research articles and review articles in all areas of nursing research and education. The aim of the journal is to contribute to the growing field of nursing practice and provide a platform for researchers, physicians and healthcare professionals. Topics of interest include:<br />1. Medical surgical nursing<br />2. Emergency nursing<br />3. Community health nursing<br />4. Mental health nursing<br />5. Gerontic nursing<br />6. Pediatric nursing<br />7. Maternity nursing<br />8. Nursing leadership and management</p> <p style="text-align: justify;">The writings can be published in this journal can be shaped in article, research reports, case study, and scientific papers. Published 3 (third) times a year, every March, July, and November.</p> https://mhjns.widyagamahusada.ac.id/index.php/mhjns/article/view/941 2026-06-30T09:29:28+07:00 Geovani R Lubu Pati geovanirambulubupati@gmail.com Previta Zeizar Rahmawati geovanirambulubupati@gmail.com

<p><em>Background: Typhoid fever is a systemic infection caused by Salmonella typhi that leads to hematological abnormalities, including thrombocytopenia and relative lymphocytosis, due to the effects of endotoxins on bone marrow. The Widal test is still widely used as a serological examination in primary health care; however, the correlation between Widal titer and hematological parameters remains inconsistent. Objective: To analyze the correlation between Widal antibody titer and lymphocyte and platelet counts in patients with typhoid fever at Puskesmas. Methods: This was a retrospective cross-sectional analytical observational design. Data were obtained from the medical records of typhoid fever patients at Puskesmas Dau from January to December 2024. Samples were selected using purposive sampling based on inclusion criteria: patients with typhoid fever who had results for Widal titers O, H, PA, PB, lymphocyte and platelet count, and complete medical records. Exclusion criteria included patients with other diagnoses, such as dengue fever and incomplete data. Data analysis was performed using Spearman’s Rank Correlation test with a significance level of p &lt; 0.05. Results: The results showed no significant correlation between Widal titer and lymphocyte count, but a significant negative correlation between Widal titer and platelet count, with r = -0.146 and p = 0.039 [p &lt; 0.05]. This indicates that higher the Widal titer, the lower the platelet count tends to be. Conclusion: There is no correlation between Widal titer and lymphocyte count. There is a significant but very weak negative correlation between Widal titer and platelet count in typhoid fever. These findings are consistent with the pathophysiology of typhoid fever, specifically thrombocytopenia resulting from the effect of S. Typhien dotoxin on bone marrow.</em></p>

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